To reduce potential confounding effects in the comparison between patients who received semaglutide and those who received dulaglutide, we estimated a propensity score (PS) using a logistic regression model adjusted for all covariates
The researchers reported improvement in more than 80% of the patients, but there was no control group
Whilst fatty liver disease itself may not directly cause B12 deficiency, the constellation of metabolic conditions, medications, and lifestyle factors commonly associated with fatty liver can collectively increase vulnerability to deficiency
Yangyang Liu, et al
Following the 80/20 rule (a common lifestyle principle that advises 80% of food from nutrient-dense, whole foods, and the remaining 20% for less nutritious options) still allows for flexibility, but every meal should ideally be nutrient-dense to prevent deficiencies and loss of muscle mass
The quite unexpected positive cardiorenal outcomes that have emerged from the cardiovascular outcomes trials (CVOTs) with both glucagon like peptide-1 receptors agonists (GLP-1RA) and sodium-glucose co-transporter 2 (SGLT-2) inhibitors have produced a shift of diabetes management from the meticulous glycemic control alone to the simultaneous improvement of CV outcomes
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