Citation: Sikiric, P., Seiwerth, S., Rucman, R., Kolenc, D., Rokotov, D., Brcic, I.,
But the jump from C57BL/6 mice to humans involves differences in metabolic rate, NNMT tissue distribution, adipose tissue physiology, and drug metabolism that preclinical data cannot address
Once youre comfortable and you can move well, youre good to go
Although no human studies have shown a negative impact on semen parameters, animal studies have shown damage to testicular sperm cells
But interesting biology and plausible mechanisms are where drug development begins, not ends
Analytical testing methods provide definitive degradation assessment but require specialized equipment