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subtilis , Fur-regulated flavodoxins YkuNOP are expressed upon iron starvation and are also likely to replace another Fur-regulated enzyme involved in energy metabolism, ferredoxin

Whats more, insulin signaling loss, noted as impaired glucose transport (alterations in the expression and trafficking of GLUT4), has been proposed to be an early pathogenic factor of AF pathogenesis (Yazici and Sezer, 2017)

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doi: 10.1016/j.biopha.2017.04.057