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proposed that the research on the treatment for immune-mediated diseases, such as rheumatoid arthritis, should attempt to achieve a more comprehensive understanding of various disease-related biomarkers, conducting large-scale high-throughput data analysis, and identifying and quantifying the disease metabolites ( 4 Disorders of fatty acid metabolism promote the development of gouty arthritis A diagram illustrating the relationship between gouty arthritis and immunity ( Figure 1 )

The absorbance at 405 nm was monitored at every 30 sec for 10 min at 37C to provide calibration curve

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Blood cell responses and metallothionein in the liver, kidney and muscles of bullfrog tadpoles, Lithobates catesbeianus, following exposure to different metals