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Regular follow-up appointments provide opportunities to discuss side effects, assess treatment efficacy, and make necessary adjustments to optimise both therapeutic benefit and tolerability

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On April 28, 2026, the FDA announced two successful proof-of-concept real-time trials in which sponsors report endpoints and data signals to the agency as they occur, instead of collecting, analyzing, and submitting data in batches

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This is where a lot of people get tripped up, but the calculations are actually quite simple once you get the hang of it