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This includes heavy lifting, repetitive motions, and excessive typing or writing

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Am J Physiol Heart Circ Physiol 285:H875H882 Irvine JC, Favaloro JL, Kemp-Harper BK (2003) NO- activates soluble guanylate cyclase and Kv channels to vasodilate resistance arteries

Some users describe improvements in pain or mobility within days or weeks, but individual responses vary widely