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However, given high GLP-1 costs and discontinuation rates, success among even a modest proportion of individuals could greatly augment overall efficacy and cost-effectiveness of GLP-1 therapy

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Nucleosomes suppress the formation of double-strand DNA breaks during attempted base excision repair of clustered oxidative damages

When food is eaten, the intestine releases GLP-1, which increases insulin secretion in response to the meal, helps lower blood sugar, slows the rate at which the stomach empties, and acts on the brainstem and hypothalamus to reduce appetite and increase fullness