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Many 50 mg and 100 mg research vials are small-format 2 mL or 3 mL nominal capacity and cannot accept 5 mL or 10 mL of diluent regardless of what a chart says

Everything below explains what it means and why context matters

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The pattern repeats with each subsequent dose increase: a brief period of adjustment followed by adaptation

Testing must therefore characterize both the formulation (assay, purity, pH, osmolality, viscosity, microbial safety) and the device performance (spray pattern, plume geometry, droplet size distribution, dose uniformity, priming behavior) as an integrated system

Until the FDA takes one of these steps, the committee vote should not be read as nationwide permission to make or dispense these peptides