Cagrilintide and retatrutide are two investigational peptide-based medicines currently being studied for the treatment of obesity and related metabolic conditions
Figure 1 gives an overview of the physiological actions of GLP-1 and GIP on various organ systems (47)
The liver accumulates scar tissue, loses its ability to function properly, and may eventually develop cirrhosis
--- ## Retatrutide FDA Approval Timeline: What to Expect As of July 2026, Eli Lilly's TRIUMPH Phase 3 program is underway with four trials (TRIUMPH-1 through TRIUMPH-4) covering obesity, type 2 diabetes, and metabolic dysfunction-associated steatohepatitis (MASH)
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