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Discovery of AG-270, a first-in-class oral MAT2A inhibitor for the treatment of tumors with homozygous MTAP deletion

They want to get their hands on any advantage in performance an athlete can access

This does two things: Keeps NAD+ precursors available for actual NAD+ synthesis Depletes the methyl groups that fat cells use to maintain their metabolic "off" state The second effect is the more interesting one

SS-31 addresses the cellular energy component

But the population of people who have taken BPC-157 outside research settings has not been followed for the kind of duration that would resolve the question, and Kekic is unambiguous about what that means for her clinical practice