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As a direct outcome of the reform, two FRPs were introduced in Australia, which are the main focus of this review

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Overall, anti-metabolic drugs performed the best in both aspects, with odds ratios of 2.15 and 1.35, while anti-fibrotic drugs showed ratios of 0.86 and 1.11

Mitochondrial abnormalities are another hallmark of cystinosis, with studies demonstrating reduced ATP production and evidence of metabolic imbalances [144, 146, 148]

Australia Research into Melanotan 1 has focused on its role in stimulating melanin production by binding to melanocortin receptors in skin cells