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The trade-off is larger injection volumes at standard doses: a 2.5mg dose requires 75 units, and a 5mg dose requires 150 units (two syringe draws)

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The B12 component supports the increased energy demands of an optimized metabolism

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Finally, designing advanced nanocarriers with improved stability, controlled release, and enhanced tumor penetration will further accelerate the clinical translation of GSH-responsive nanomedicine

1999 Jul;94(7):1818-22