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Description

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To further test the hypothesis that Barr1 is required for SU-mediated Epac2 activation, we performed additional islet perifusion studies using a specific Epac2 inhibitor, ESI-05 (25)

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Furthermore, 18.5 l of 1 M potassium hydroxide, 30 l of 150 mM monopotassium phosphate (KH2PO4)/150 mM potassium chloride (KCl) solution (Ph 6.0) and 0.5% acetonitrile were added

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