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GLP-1 users are not anti-alcohol, they are anti-excess, explains Leigh ODonnell, head of shopper and category insights at Kantar

Glucagon-like peptide-1 receptor agonists (GLP-1a) act on numerous pathways that intersect glycemic, weight, and blood pressure (BP) control

We recommend using the smallest appropriate gauge, typically 23-25g

Although the human relevance of these findings remains uncertain, as human C-cells have lower GLP-1 receptor expression compared to rodents, the potential risk necessitates avoiding this medication in patients with any personal or family history of medullary thyroid carcinoma

This is the same basic mechanism as acarbose- a prescribed diabetes medication- achieved through dietary compounds

310 Similar effects are observed after transgenic deletion of Ccl2 specifically from astrocytes, which showed little effects early in EAE but demonstrated that astrocyte Ccl2 sustains disease symptoms and inflammation during chronic EAE, making it a therapeutic target