[ 4] In addition to helping people lose weight, there is a lot of emerging data that GLP-1 agonists may significantly reduce the risk of heart attacks and strokes in patients with a history of cardiovascular disease by as much as 20%
The best choice for you depends on your specific goals and needs
Physiological melanin hyperpigmentation does not require treatment, but if for cosmetic reasons it has to be removed, laser or cryotherapy or surgical excision are often successful

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Ruggiero-Lopez D, Lecomte M, Moinet G, Patereau G, Lagarde M, Wiernsperger N (1999) Reaction of metformin with dicarbonyl compounds
This treatment is safe for all skin types, has no downtime, and can be used as a maintenance therapy alongside other medical treatments for melasma