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7 Affected animals display loose and extremely fragile skin (dermatosparaxis means tearing of the skin), resulting in large skin lacerations during delivery or early in life, with subsequent infections and premature death

3 Results 3.1 Descriptive analysis of included studies The analysis of the included studies provides valuable insights into the field's research landscape

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Specifically, an imbalance between oxidants and antioxidants, increased ROS production, a reduction in antioxidant enzymes function contribute to the pathogenesis and development of psoriasis [3]

this hypothesis is also given credence by the common finding of GSTP overexpression in tumor cell lines that are not drug resistant