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Peak effects occur approximately 2-3 hours post-administration with duration of action extending 6-12 hours

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10.1016/j.cell.2015.10.034 Cell 64 HarrisR

Individuals harbor vastly different communities and abundances of myrosinase-producing bacteria (e.g., certain strains of Bacteroides, Enterococcus, and Lactobacillus), leading to profound differences in the efficiency of SFN generation ( 3.3 Host genetics: GST polymorphisms and metabolic destiny Beyond microbial activation, host genetics, particularly polymorphisms in GST genes, play a decisive role in shaping SFNs metabolic fate and tissue retention