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RTqPCR revealed expression of the hepatic markers A1AT , AFP, ALB , and ASGR1 as well as genes enriched in the liver such as APOA2 , TDO2 and TTR and xenobiotic metabolism, cytochrome P450 ( CYP) 3A4 and CYP3A7 (Supplementary Fig

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What the Research Says About Safety Clinical studies on AOD9604 indicate that the peptide is generally welltolerated: In human trials, no significant adverse effects were reported at doses up to 1 mg/day (safety summary) Unlike growth hormone therapies, AOD9604 does not meaningfully elevate IGF1 levels (human data), which may reduce the risk of unwanted growthrelated side effects

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