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Leading symptoms of carnitine deficiency include muscle weakness alternating with muscle cramps, fatigue, hypotension, and cardiac disorders such as arrhythmias, and abnormal laboratory findings related to serum lipids and chronic inflammation parameters (C-reactive protein) as well as insulin resistance [4]

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For the metabolomic analysis, 100 L of serum were mixed with 400 L of extraction solvent (methanol:acetonitrile:acetone = 1:1:1, v/v)

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Cancer Sci 109:611617 Mauseth B, Camilio KA, Shi J, Hammarstrm CL, Rekdal , Sveinbjrnsson B, Line P-D (2019) The novel oncolytic compound LTX-401 induces antitumor immune responses in experimental hepatocellular carcinoma