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Conclusion While the cost of GLP-1 medications can be overwhelming, exploring these alternative strategies can provide safe and effective ways to manage diabetes and obesity without resorting to compounded medications

Animal model research suggests the combination produces a larger GH pulse than either compound alone

Thus, initially sermorelin results in an additive effect on endogenous GHRH receptors, but after several weeks or months, the absence of natural GHRH and desensitized GHRH receptors blunt the initial response

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