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Discard any unused portion immediately

Symptoms can include: decreased urination swelling in legs and ankles confusion fatigue Increased low-density lipoprotein cholesterol levels Other serious side effects, explained in more detail below in Side effect details, include: Ketoacidosis (buildup of ketones in the body, causing your blood to be too acidic) Serious urinary tract infections (including urosepsis and pyelonephritis) Fourniers gangrene (severe infection near the genitals) Genital yeast infection Serious allergic reactions Side effect details You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it

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The addition of glucagon receptor agonism to the GLP-1/GIP dual mechanism significantly increases energy expenditure and fat oxidation, producing weight loss potential that exceeds even tirzepatide

Never adjust your dose outside of medical supervision

Patients received once-daily orforglipron (6, 12, or 36 mg) or placebo for 72 weeks