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In the position of the Working Group for Apheresis of the Polish Society of Nephrology [268] which was widely discussed and criticised at many sites, other (in addition to HoFH and HeFH) indications for treatment with LDL-apheresis have also been listed: Primary prevention of cardiovascular disease: in patients with documented risk factors for coronary artery disease or its equivalent (e.g

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K m and k cat values were determined for the investigated monophenolic (tyramine and L -tyrosine) and diphenolic substrates (dopamine and L -DOPA)

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