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To understand how central carbon metabolism may be rewired to support purine nucleotide synthesis, we performed 13 C-glucose tracing experiments, which confirmed that CR hi cell lines had significant enrichment of 13 C into tricarboxylic acid intermediates (Figure 8B and Supplemental Figure 6, AD)
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"They're still flogging this dead horse trying to get it up." These days, a perfect John Carpenter Night for Carpenter at least probably involves more Los Angeles Lakers and Call of Duty on his TV screen than horror films
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