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Adults 18 and over BMI 24.9 or less: No BMI 25-26.9: Case-by-case** BMI 27-29.9: Likely** BMI 30 or above: Likely Your prescriber will approve or disapprove the GLP-1 prescription at their discretion after careful consideration of your unique health profile

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Therefore, although DPP-4 inhibitors have attractive clinical features, the benefits that might be expected from GLP-1 signaling may be undermined by their actions to enhance SDF-1

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