The blood pressure-lowering effect appears to be driven primarily by weight loss (patients in the STEP trials lost 10-15% of body weight), though improvements in insulin sensitivity and vascular function may also contribute
So when I tried to give up on my career
Clinical trials did not specify a relationship to meals, and absorption occurs through subcutaneous tissue, not the GI tract, so food in your stomach has no direct effect on how the drug enters your bloodstream
Commonly reported side effects for this medication class include nausea, vomiting, diarrhea, and constipation, along with more serious considerations such as pancreatitis risk, thyroid C-cell tumor boxed-warning language, and contraindications for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2
After looking into Wegovy, having guidance kept me motivated through slower weeks
This might be what makes all the difference in the speed and degree of weight loss
