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A few studies have reported that lack of the endogenous antioxidant enzymes correlates to development of colitis and colon cancer, while increased activity of antioxidant enzymes in the colon effectively reduces oxidative stress-induced colonic tissue damage (58)

Mechanistically, GHK-Cu has been shown to stimulate collagen and elastin synthesis in dermal fibroblasts, increase decorin (a small proteoglycan that helps regulate collagen organization), and influence matrix metalloproteinases and their inhibitors

Some people may experience mild digestive upset if they take standard capsules, though liposomal versions are often gentler on the stomach

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Gut microbiota in patients with polycystic ovary syndrome: A systematic review