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After that initial period, it is common to continue injections monthly, though less frequent intervals might be OK if cobalamin blood levels are supportive

In particular, glutathione (GSH) depletion is a common feature of apoptotic cell death triggered by a wide variety of stimuli including activation of death receptors, stress, environmental agents, and cytotoxic drugs

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doi: 10.3389/fmicb.2019.02324 269 RaphaelINalawadeSEagarTNForsthuberTG