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When to seek medical attention: Severe or persistent abdominal pain (stop medication and seek urgent carepotential pancreatitis) Persistent nausea or vomiting affecting hydration or nutrition Signs of gallbladder disease (right upper quadrant pain) Symptoms of hypoglycaemia if taking other diabetes medications No weight loss after 3 months at maintenance dose Regular monitoring, including weight, waist circumference, blood pressure, and metabolic parameters, should be conducted throughout treatment to assess efficacy and safety