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3.5 Cancers Currently, metabolic rewiring, which supports unrestricted proliferation and metastatic progression of cancer cells, is widely accepted to be an emerging hallmark of cancers (Petvri et al., 2020)

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Research interest areas that appear in the scientific literature include: Muscle protein synthesis and body composition changes in adults with GH deficiency Recovery from musculoskeletal injury given GHs role in tissue repair Sleep quality, given GHs relationship to slow-wave sleep architecture Metabolic function, particularly lean mass preservation in aging populations Important caveat: most human studies are small, short-term, and conducted in specific populations (often GH-deficient patients)