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In cell culture studies, addition of epitalon to telomerase-negative human fetal fibroblasts induced expression of this catalytical subunit, enzymatic telomerase activity, and subsequent telomere elongation
The active factor turned out to be a tiny tripeptide: glycyl-L-histidyl-L-lysine, bound to a copper ion
However, as reassuring as all of this is, there are a couple of things to remain mindful of: Copper toxicity Because GHK-Cu contains copper, it does pose a potential risk of copper toxicity,12 the symptoms of which include abdominal pain, vomiting, chest pain, chills, cough, fever, general weakness, anemia, burning sensations, tremors, and a metallic taste in the mouth.13 The risk is small, as the concentrations of copper in the peptide are typically well within safe parameters, but its good to be aware of it
[DOI] [PubMed] [Google Scholar] 29.Liu X., Wang L., Cai J., Liu K., Liu M., Wang H., Zhang H
It combines direct natural chelatorssubstances that physically bind to heavy metal ionswith powerful intracellular antioxidants that repair the cellular damage caused by toxic exposure
Over the past year, the short and long basket actually have a decent correlation (0.779) so this could prove to be a good collection for L/S based on this single factor
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