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Clinical evidence from the STEP trials demonstrated that higher doses produce greater weight loss, with the 2.4 mg dose resulting in approximately 15% body weight reduction over 68 weeks compared to placebo

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In fact, some studies found that semaglutide (GLP-1 RA) medications helped people lose an average of 9%-17% of their body weight in a little over a year

Later, its label was expanded, through an FDA approval, to include a reduction in the risk of major heart events in the same group

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