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Consider more frequent checks during dose titration based on clinical judgement

In humans, L585 cleavage by CPA reduces the plasma half-life of albumin from 3 weeks to 3.5 days due to loss of FcRn binding affinity 60

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Our CR-induced metabolic reprogramming and multi-cellular competition models suggest plausible dysregulation of genes, networks, and pathways of pre-malignant and malignant states