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Future studies should aim to replicate the findings, ideally with a larger sample size to increase statistical power
In TRIUMPH-4, participants with obesity and knee osteoarthritis taking retatrutide 12 mg lost ~28.7% of body weight (~71 lbs at 68 weeks) and saw substantial improvements in pain and function: WOMAC pain scores reduced by 4.5 points (75.8%) Meaningful gains in physical function, with many patients essentially free of knee pain by study end If these results are confirmed in broader use, were not just talking about weight loss drugs anymorewere talking about disease-modifying therapies that simultaneously target obesity, pain, mobility, and downstream CV risk
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Brinker F
On March 4, 2022, FDA authorized an extension (PDF, 33 KB) for the shelf life of the refrigerated Janssen COVID-19 Vaccine, allowing the product to be stored at 2-8 degrees Celsius for 9 months
Compounded semaglutide is now offered by countless providers many of them online, faceless, and lacking real medical oversight
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