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These predictive models should be interpreted cautiously and not equated with confirmed metabolic outputs

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doi:10.1177/15563316251355551 Gwyer D, Wragg NM, Wilson SL

Unrealised Expectations Despite progress, several anticipated 2025 milestones did not come to fruition: Regulatory progress stalled: FDAs obesity drug guidance, published in draft form in January 2025, remains unfinalised, whilst EMA has yet to update its 2016 guideline

No clinical evidence shows that GLP-1 receptor agonists damage or stress the remaining bile ducts or liver after cholecystectomy