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If these benefits are confirmed in large trials, retatrutide could represent a significant advance in the treatment of chronic metabolic disease

The first four are acetylcholine esterase inhibitors (AchEIs), while the fifth is an N-methyl-D-aspartate receptor antagonist (NMDARA)

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Its plasma levels decline significantly with age (from ~200ng/mL at 20 to ~80ng/mL at 60), making it a key compound for aging biology and regenerative research

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