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Antioxidant Supplementation on Male Fertility-A Systematic Review

at this moment, NFR-2 translocates to the nucleus, in order to dimerize and bind to its corresponding promotor regions to regulate the transcription of the antioxidant response element [20,21]

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Nat Cell Bio

Expression of a non-native redox sensor might not reflect the natural redox state in the periplasm or might even influence it by diverting oxidative power available for the formation of native disulfide bonds