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While sulphonylureas potently promote insulin secretion in type-2 diabetic patients via inhibition of K ATP channel activity [[267], [268], [269], [270]], there is no clear evidence that sulphonylureas affect GLP-1 secretion in humans (as reviewed in [266])

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Taken together, MSCs cultured under cell culture densities that prime MSCs to possess high levels of GSH could potentiate the regeneration capacity of the articular cartilage at chondral defect sites, leading to smooth and uniform hyaline cartilage formation