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DTrp2 also had no opioid receptor activity and was specific in action in that it did not release thyrotropin-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), or adrenocorticotropic hormone (ACTH), all of which derive from the pituitary gland

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The disorder can often lead to coma and death

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doi: 10.1038/s41598-018-23420-4 28 TianJZhangMSuoMLiuDWangXLiuMet al