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PROTAC-Mediated HDAC7 protein degradation unveils its deacetylase-independent proinflammatory function in macrophages

Nature Cell Biology DOI:10.1038/s41556-026-01922-y Abstract SLC33A1 exports oxidized glutathione to maintain endoplasmic reticulum redox homeostasis The endoplasmic reticulum (ER) requires an oxidative environment to support the efficient maturation of secretory and membrane proteins

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Keep tightly capped and stored in a cool, dry place for optimal freshness.*These statements have not been evaluated by the Food and Drug Administration