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Much of the metabolic research is still preclinical, but the mechanism makes it a useful tool for patients whose weight loss resistance is rooted in insulin resistance or mitochondrial inefficiency

In rodent studies, animals with greater GLUT4 expression display heightened insulin sensitivity, whereas those with reduced GLUT4 levels demonstrate impaired insulin signaling

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People are encouraged to consult with their healthcare team and prepare alternative management plans appropriately before the change takes effect in October