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Lastly, among rats, the administration of wortmannin (a fungal metabolite) which induces hyperphosphorylation of tau in hippocampal pyramidal neurons, can be partly attenuated by preinjection of melatonin [117, 118], underscoring melatonins potential therapeutic role

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Chloroquine, a FDA-approved drug, prevents Zika virus infection and its associated congenital microcephaly in mice

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