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10.3390/ph14100979 Pharmaceuticals

The FDA added a safety review in 2024 to examine potential neuropsychiatric effects across the entire GLP-1 class, including semaglutide and tirzepatide

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Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole-kindled mice

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without a GLP-1 receptor agonist prescription had a significantly decreased risk for this outcome at 5 years (RR = 0.72