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8 weeks: ~3 vials (~2.24 mg) 12 weeks: ~4 vials (~3.64 mg) 16 weeks: ~6 vials (~5.04 mg) Insulin Syringes (U-100, 0.5 mL or 1 mL) Per injection: 1 syringe 8 weeks (once daily): ~56 syringes 16 weeks (once daily): ~112 syringes Bacteriostatic Water (10 mL bottles) Use 3.0 mL per 1 mg vial for reconstitution

Discontinuation rates across trials: Retatrutides discontinuation rate in the general obesity population (11.3%) is higher than its approved competitors

BioWorld Regulatory Obesity Small molecule Europe Danish Medicines Agency EMA

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Ashley Dunham decided she wanted bariatric surgery last June when she "hit rock bottom" and felt she could no longer control her weight