[DOI] [PMC free article] [PubMed] [Google Scholar] 118.Liou C.-J., Wei C.-H., Chen Y.-L., Cheng C.-Y., Wang C.-L., Huang W.-C
New or worsening symptoms after months of stable semaglutide therapy should also prompt evaluation, as these may not be medication-related
What the evidence does show is that semaglutide tends to lower systolic blood pressure modestly while raising heart rate slightly, and that people with hypertension are frequently on medications whose absorption or effect warrants attention when gastric emptying slows
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