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In a cerebrospinal fluid (CSF) substudy, participants receiving semaglutide exhibited modest yet statistically significant reductions (in the range of 10% or less) in several key biomarkers associated with Alzheimers disease (AD) pathology and neurodegeneration, including phosphorylated tau181 (p-tau181), phosphorylated tau217 (p-tau217), total tau, and the neuroinflammatory marker YKL-40 levels

Primer sequences are provided in Table 2

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There are a lot of success stories like mine, which means there has been a lot of chatter and excitement about these drugs

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