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Fasting glucose, HbA1c, triglycerides, liver function, and kidney markers help identify whether metabolic improvement is occurring and whether dose escalation is necessary

Simultaneously, hydrogen selenide (H 2 Se) generated from the metabolism of dietary selenium species is converted into selenophosphate (H 2 SePO 3 ) by the enzyme selenophosphate synthetase 2 (SEPHS2) which is then used as a substrate by the enzyme O-phosphoseryl-tRNA [Ser]Sec selenium transferase to incorporate selenium into phosphoseryl-tRNA [Ser]Sec to form Sec-tRNA [ser]sec

Journal of Trace Elements in Medicine and Biology

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392:427-437 [PubMed: 39555826] 401

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