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Kobulia B, Chapichadze Z Andriadze G Machavariani P

Association of social and cognitive impairment and biomarkers in autism spectrum disorders

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The compound works by binding to the ghrelin receptor, which stimulates the pituitary gland to secrete growth hormone into the bloodstream

Compared to exogenous recombinant GH (somatropin), Tesamorelin preserves the physiological pulsatility of endogenous secretion, maintaining better tissue response, avoiding GH-R desensitization, and presenting a more balanced metabolic profile (glycemic neutrality vs diabetogenic effect often documented with high-dose exogenous GH)