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All of them put together make us think that the systemic risks are very, very contained

Felix JB, Cox AR, Hartig SM

10.3969/j.issn.1671-3141.2016.105.152(in Chinese)

Every day exposure to stress, air pollution, cigarette smoke, medications, and certain foods increases the formation of these free radicals in cells

Safety in TRIUMPH-1 The safety profile was consistent with incretin-class therapies: Most common AEs (12 mg dose): - Nausea: 42.4% - Diarrhea: 32.0% - Constipation: 26.1% - Vomiting: 25.3% Dysesthesia (a sensory disturbance tingling, numbness) and urinary tract infections were reported in approximately 10% of patients on the highest doses, but were generally mild to moderate and mostly resolved during treatment

A Cochrane systematic review of 63 RCTs (N=11,811) found that Lactobacillus rhamnosus GG and Saccharomyces boulardii reduced the risk of antibiotic-associated diarrhea by 42% relative to placebo (RR 0.58 to 95% CI 0.50 to 0.68) 18