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Intravenous administration of direct NAD + has been carried out in humans 66,116,117 , but the human trials were conducted in extremely small cohorts
Medical News Today, August 2018
Although thiamine deficiency is rare in developed countries, it can lead to severe neurological disorders, emphasizing the importance of adequate thiamine intake for optimal health and as treatment when administered promptly ( 3 Vitamin B2 Vitamin B2, also known as riboflavin, is predominantly found in milk and dairy products, as well as in organ meats such as liver and kidneys (44, 45)
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