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However, the evolutionary and physiological relevance of such phenomena and the underlying molecular mechanisms remain unclear

Yanai H, Adachi H, Hamasaki H, Masui Y, Yoshikawa R, Moriyama S, Mishima S, Sako A: Effects of 6-month sitagliptin treatment on glucose and lipid metabolism, blood pressure, body weight and renal function in type 2 diabetic patients: a chart-based analysis

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In addition, mitochondria also produce a large amount of ROS during normal metabolism and the generation of cellular energy via the electron transport chain, leading to cell and tissue damage [36]

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[IMAGE 2: Saxenda dose titration diagram, original WebP base64 here] How effective is Saxenda for weight loss